AUTOINFLAMMATORY DISEASE

A group of rare conditions including hereditary fever syndromes, autoinflammatory diseases are the result of mutations in genes that are involved in regulating the innate immune system. The innate immune system is the primal initial line of defense against viruses, bacteria and other microorganisms. When the innate immune system goes unchecked, patients can have recurrent noninfectious fever, inflammatory rashes, joint pain, enlarged and inflamed abdominal organs. These are uncommon conditions that require a high index of clinical suspicion and good detective work in order to diagnose.
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